diff --git a/src/calibre/gui2/__init__.py b/src/calibre/gui2/__init__.py
index 47262bbaa7..78261d97fc 100644
--- a/src/calibre/gui2/__init__.py
+++ b/src/calibre/gui2/__init__.py
@@ -19,6 +19,7 @@ from qt.core import (
 )
 from threading import Lock, RLock
 
+import calibre.gui2.pyqt6_compat as pqc
 from calibre import as_unicode, prints
 from calibre.constants import (
     DEBUG, __appname__ as APP_UID, __version__, config_dir, filesystem_encoding,
@@ -39,6 +40,7 @@ from calibre.utils.localization import get_lang
 from polyglot import queue
 from polyglot.builtins import iteritems, itervalues, string_or_bytes
 
+del pqc
 try:
     NO_URL_FORMATTING = QUrl.UrlFormattingOption.None_
 except AttributeError:
diff --git a/src/calibre/gui2/gestures.py b/src/calibre/gui2/gestures.py
index cf45d98bd3..135797eb55 100644
--- a/src/calibre/gui2/gestures.py
+++ b/src/calibre/gui2/gestures.py
@@ -5,8 +5,8 @@
 import os
 from functools import lru_cache
 from qt.core import (
-    QApplication, QEvent, QMouseEvent, QObject, QPointF, QScroller, Qt, QInputDevice,
-    pyqtSignal
+    QApplication, QEvent, QInputDevice, QMouseEvent, QObject, QPointF,
+    QPointingDevice, QScroller, Qt, pyqtSignal
 )
 
 from calibre.utils.monotonic import monotonic
@@ -174,7 +174,7 @@ class GestureManager(QObject):
             return
         etype = ev.type()
         if etype in (QEvent.Type.MouseButtonPress, QEvent.Type.MouseMove, QEvent.Type.MouseButtonRelease, QEvent.Type.MouseButtonDblClick):
-            if ev.source() in (Qt.MouseEventSource.MouseEventSynthesizedBySystem, Qt.MouseEventSource.MouseEventSynthesizedByQt):
+            if ev.pointingDevice().pointerType() is QPointingDevice.PointerType.Finger:
                 # swallow fake mouse events generated from touch events
                 ev.ignore()
                 return False
diff --git a/src/calibre/gui2/pyqt6_compat.py b/src/calibre/gui2/pyqt6_compat.py
new file mode 100644
index 0000000000..3807d897c2
--- /dev/null
+++ b/src/calibre/gui2/pyqt6_compat.py
@@ -0,0 +1,20 @@
+#!/usr/bin/env python
+# vim:fileencoding=utf-8
+# License: GPL v3 Copyright: 2021, Kovid Goyal <kovid at kovidgoyal.net>
+
+# Workaround a bunch of brain dead changes in PyQt6 that break backwards compat
+# for no good reason. Since we have a huge body of poorly maintained third
+# party plugin code, we NEED backward compat.
+
+from qt.core import QSinglePointEvent
+
+
+# Restore removed functions from QMouseEvent
+QSinglePointEvent.x = lambda self: int(self.position().x())
+QSinglePointEvent.y = lambda self: int(self.position().y())
+QSinglePointEvent.globalPos = lambda self: self.globalPosition.toPoint()
+QSinglePointEvent.globalX = lambda self: self.globalPosition.toPoint().x()
+QSinglePointEvent.globalY = lambda self: self.globalPosition.toPoint().y()
+QSinglePointEvent.localPos = lambda self: self.position()
+QSinglePointEvent.screenPos = lambda self: self.globalPosition()
+QSinglePointEvent.windowPos = lambda self: self.scenePosition()