diff --git a/setup/__init__.py b/setup/__init__.py
index d8b32ba677..6a45395fc2 100644
--- a/setup/__init__.py
+++ b/setup/__init__.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__   = 'GPL v3'
@@ -92,7 +91,7 @@ def build_cache_dir():
         _cache_dir_built = True
         try:
             os.mkdir(ans)
-        except EnvironmentError as err:
+        except OSError as err:
             if err.errno != errno.EEXIST:
                 raise
     return ans
@@ -100,7 +99,7 @@ def build_cache_dir():
 
 def require_git_master(branch='master'):
     if subprocess.check_output(['git', 'symbolic-ref', '--short', 'HEAD']).decode('utf-8').strip() != branch:
-        raise SystemExit('You must be in the {} git branch'.format(branch))
+        raise SystemExit(f'You must be in the {branch} git branch')
 
 
 def require_clean_git():
@@ -225,7 +224,7 @@ class Command:
         st = time.time()
         self.running(cmd)
         cmd.run(opts)
-        self.info('* %s took %.1f seconds' % (command_names[cmd], time.time() - st))
+        self.info(f'* {command_names[cmd]} took {time.time() - st:.1f} seconds')
         if os.environ.get('CI'):
             self.info('::endgroup::')
 
diff --git a/setup/browser_data.py b/setup/browser_data.py
index 6b17747857..3904feb883 100644
--- a/setup/browser_data.py
+++ b/setup/browser_data.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2017, Kovid Goyal <kovid at kovidgoyal.net>
 
 
diff --git a/setup/build.py b/setup/build.py
index b0b093e2f9..aa1013c188 100644
--- a/setup/build.py
+++ b/setup/build.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 __license__   = 'GPL v3'
 __copyright__ = '2009, Kovid Goyal <kovid@kovidgoyal.net>'
@@ -28,7 +27,7 @@ def init_symbol_name(name):
 
 
 def absolutize(paths):
-    return list(set([x if os.path.isabs(x) else os.path.join(SRC, x.replace('/', os.sep)) for x in paths]))
+    return list({x if os.path.isabs(x) else os.path.join(SRC, x.replace('/', os.sep)) for x in paths})
 
 
 class Extension:
diff --git a/setup/build_environment.py b/setup/build_environment.py
index d40842e2cd..fb5135612e 100644
--- a/setup/build_environment.py
+++ b/setup/build_environment.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__   = 'GPL v3'
diff --git a/setup/changelog.py b/setup/changelog.py
index 691042be1a..ff37888f21 100644
--- a/setup/changelog.py
+++ b/setup/changelog.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPL v3 Copyright: 2020, Kovid Goyal <kovid at kovidgoyal.net>
 
 from datetime import date
diff --git a/setup/check.py b/setup/check.py
index 176afb1b98..f3e9e7a307 100644
--- a/setup/check.py
+++ b/setup/check.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__   = 'GPL v3'
@@ -16,7 +15,7 @@ class Message:
         self.filename, self.lineno, self.msg = filename, lineno, msg
 
     def __str__(self):
-        return '%s:%s: %s' % (self.filename, self.lineno, self.msg)
+        return f'{self.filename}:{self.lineno}: {self.msg}'
 
 
 def checkable_python_files(SRC):
@@ -95,7 +94,7 @@ class Check(Command):
         try:
             with open(self.cache_file, 'rb') as f:
                 cache = json.load(f)
-        except EnvironmentError as err:
+        except OSError as err:
             if err.errno != errno.ENOENT:
                 raise
         dirty_files = tuple(f for f in self.get_files() if not self.is_cache_valid(f, cache))
@@ -118,7 +117,7 @@ class Check(Command):
     def clean(self):
         try:
             os.remove(self.cache_file)
-        except EnvironmentError as err:
+        except OSError as err:
             if err.errno != errno.ENOENT:
                 raise
 
@@ -129,6 +128,10 @@ class UpgradeSourceCode(Command):
 
     def run(self, opts):
         files = []
+        for f in os.listdir(os.path.dirname(os.path.abspath(__file__))):
+            q = os.path.join('setup', f)
+            if f.endswith('.py') and f not in ('linux-installer.py',) and not os.path.isdir(q):
+                files.append(q)
         for path in checkable_python_files(self.SRC):
             q = path.replace(os.sep, '/')
             if '/metadata/sources/' in q or '/store/stores/' in q:
diff --git a/setup/commands.py b/setup/commands.py
index 4b34fb5a07..b095e31024 100644
--- a/setup/commands.py
+++ b/setup/commands.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__   = 'GPL v3'
diff --git a/setup/csslint.py b/setup/csslint.py
index 97b493829b..4461f3d102 100644
--- a/setup/csslint.py
+++ b/setup/csslint.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPL v3 Copyright: 2020, Kovid Goyal <kovid at kovidgoyal.net>
 
 import os
diff --git a/setup/file-hosting-bw.py b/setup/file-hosting-bw.py
index c6a7a34304..f2ad65c342 100644
--- a/setup/file-hosting-bw.py
+++ b/setup/file-hosting-bw.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 
 
 __license__ = 'GPL v3'
diff --git a/setup/git_post_checkout_hook.py b/setup/git_post_checkout_hook.py
index 606f59fedb..000ab43981 100755
--- a/setup/git_post_checkout_hook.py
+++ b/setup/git_post_checkout_hook.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 
 __license__ = 'GPL v3'
 __copyright__ = '2013, Kovid Goyal <kovid at kovidgoyal.net>'
diff --git a/setup/git_post_rewrite_hook.py b/setup/git_post_rewrite_hook.py
index 56ca6eadbd..79474bde86 100755
--- a/setup/git_post_rewrite_hook.py
+++ b/setup/git_post_rewrite_hook.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 
 __license__ = 'GPL v3'
 __copyright__ = '2014, Kovid Goyal <kovid at kovidgoyal.net>'
diff --git a/setup/git_pre_commit_hook.py b/setup/git_pre_commit_hook.py
index cdcfe1f633..742b88229b 100755
--- a/setup/git_pre_commit_hook.py
+++ b/setup/git_pre_commit_hook.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2008, Kovid Goyal <kovid at kovidgoyal.net>
 
 
@@ -55,7 +54,7 @@ class Bug:
             print('Working on bug:', summary)
             if int(bug) > 100000 and action != 'See':
                 self.close_bug(bug, action)
-                return match.group() + ' [%s](%s)' % (summary, LAUNCHPAD_BUG % bug)
+                return match.group() + f' [{summary}]({LAUNCHPAD_BUG % bug})'
             return match.group() + ' (%s)' % summary
         return match.group()
 
@@ -66,7 +65,7 @@ class Bug:
             'calibre is usually released every alternate Friday.'
         )
         action += 'ed'
-        msg = '%s in branch %s. %s' % (action, 'master', suffix)
+        msg = '{} in branch {}. {}'.format(action, 'master', suffix)
         msg = msg.replace('Fixesed', 'Fixed')
         msg += '\n\n status fixreleased'
 
diff --git a/setup/git_version.py b/setup/git_version.py
index 21ceebfdb7..723067223c 100755
--- a/setup/git_version.py
+++ b/setup/git_version.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2019, Eli Schwartz <eschwartz@archlinux.org>
 
 
diff --git a/setup/gui.py b/setup/gui.py
index 8405668c1b..5c88570100 100644
--- a/setup/gui.py
+++ b/setup/gui.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__   = 'GPL v3'
diff --git a/setup/hosting.py b/setup/hosting.py
index 62af0fc05e..40d065cc94 100644
--- a/setup/hosting.py
+++ b/setup/hosting.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 __license__ = 'GPL v3'
 __copyright__ = '2011, Kovid Goyal <kovid@kovidgoyal.net>'
@@ -150,7 +149,7 @@ class GitHub(Base):  # {{{
         existing_assets = self.existing_assets(release['id'])
         for path, desc in self.files.items():
             self.info('')
-            url = self.API + 'repos/%s/%s/releases/assets/{}' % (
+            url = self.API + 'repos/{}/{}/releases/assets/{{}}'.format(
                 self.username, self.reponame
             )
             fname = os.path.basename(path)
@@ -206,7 +205,7 @@ class GitHub(Base):  # {{{
 
     def do_upload(self, url, path, desc, fname):
         mime_type = mimetypes.guess_type(fname)[0] or 'application/octet-stream'
-        self.info('Uploading to GitHub: %s (%s)' % (fname, mime_type))
+        self.info(f'Uploading to GitHub: {fname} ({mime_type})')
         with ReadFileWithProgressReporting(path) as f:
             return self.requests.post(
                 url,
@@ -229,7 +228,7 @@ class GitHub(Base):  # {{{
         return error_code == 'already_exists'
 
     def existing_assets(self, release_id):
-        url = self.API + 'repos/%s/%s/releases/%s/assets' % (
+        url = self.API + 'repos/{}/{}/releases/{}/assets'.format(
             self.username, self.reponame, release_id
         )
         r = self.requests.get(url)
@@ -238,7 +237,7 @@ class GitHub(Base):  # {{{
         return {asset['name']: asset['id'] for asset in r.json()}
 
     def releases(self):
-        url = self.API + 'repos/%s/%s/releases' % (self.username, self.reponame)
+        url = self.API + f'repos/{self.username}/{self.reponame}/releases'
         r = self.requests.get(url)
         if r.status_code != 200:
             self.fail(r, 'Failed to list releases')
@@ -250,7 +249,7 @@ class GitHub(Base):  # {{{
             # Check for existing release
             if release['tag_name'] == self.current_tag_name:
                 return release
-        url = self.API + 'repos/%s/%s/releases' % (self.username, self.reponame)
+        url = self.API + f'repos/{self.username}/{self.reponame}/releases'
         r = self.requests.post(
             url,
             data=json.dumps({
@@ -275,7 +274,7 @@ def generate_index():  # {{{
     releases = set()
     for x in os.listdir('.'):
         if os.path.isdir(x) and '.' in x:
-            releases.add(tuple((int(y) for y in x.split('.'))))
+            releases.add(tuple(int(y) for y in x.split('.')))
     rmap = OrderedDict()
     for rnum in sorted(releases, reverse=True):
         series = rnum[:2] if rnum[0] == 0 else rnum[:1]
@@ -301,10 +300,10 @@ def generate_index():  # {{{
         body.append(
             '<li><a href="{0}.html" title="Releases in the {0}.x series">{0}.x</a>\xa0\xa0\xa0<span style="font-size:smaller">[{1} releases]</span></li>'
             .format(  # noqa
-                '.'.join(map(type(''), series)), len(rmap[series])
+                '.'.join(map(str, series)), len(rmap[series])
             )
         )
-    body = '<ul>{0}</ul>'.format(' '.join(body))
+    body = '<ul>{}</ul>'.format(' '.join(body))
     index = template.format(
         title='Previous calibre releases',
         style=style,
@@ -315,13 +314,13 @@ def generate_index():  # {{{
         f.write(index.encode('utf-8'))
 
     for series, releases in rmap.items():
-        sname = '.'.join(map(type(''), series))
+        sname = '.'.join(map(str, series))
         body = [
             '<li><a href="{0}/" title="Release {0}">{0}</a></li>'.format(
-                '.'.join(map(type(''), r))
+                '.'.join(map(str, r))
             ) for r in releases
         ]
-        body = '<ul class="release-list">{0}</ul>'.format(' '.join(body))
+        body = '<ul class="release-list">{}</ul>'.format(' '.join(body))
         index = template.format(
             title='Previous calibre releases (%s.x)' % sname,
             style=style,
@@ -332,7 +331,7 @@ def generate_index():  # {{{
             f.write(index.encode('utf-8'))
 
         for r in releases:
-            rname = '.'.join(map(type(''), r))
+            rname = '.'.join(map(str, r))
             os.chdir(rname)
             try:
                 body = []
@@ -346,7 +345,7 @@ def generate_index():  # {{{
                         ) for x in windows
                     ]
                     body.append(
-                        '<dt>Windows</dt><dd><ul>{0}</ul></dd>'.format(
+                        '<dt>Windows</dt><dd><ul>{}</ul></dd>'.format(
                             ' '.join(windows)
                         )
                     )
@@ -373,7 +372,7 @@ def generate_index():  # {{{
                         ) for x in linux
                     ]
                     body.append(
-                        '<dt>Linux</dt><dd><ul>{0}</ul></dd>'.format(
+                        '<dt>Linux</dt><dd><ul>{}</ul></dd>'.format(
                             ' '.join(linux)
                         )
                     )
@@ -384,7 +383,7 @@ def generate_index():  # {{{
                         .format(source[0], 'Source code (all platforms)')
                     )
 
-                body = '<dl>{0}</dl>'.format(''.join(body))
+                body = '<dl>{}</dl>'.format(''.join(body))
                 index = template.format(
                     title='calibre release (%s)' % rname,
                     style=style,
diff --git a/setup/hyphenation.py b/setup/hyphenation.py
index 6e3713ffca..66a475054f 100644
--- a/setup/hyphenation.py
+++ b/setup/hyphenation.py
@@ -1,7 +1,5 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:fdm=marker:ai
 # License: GPLv3 Copyright: 2019, Kovid Goyal <kovid at kovidgoyal.net>
-from __future__ import absolute_import, division, print_function, unicode_literals
 
 import glob
 import hashlib
@@ -100,7 +98,7 @@ class Hyphenation(ReVendor):
             for dic in dics:
                 with open(os.path.join(output_dir, dic), 'rb') as f:
                     m.update(f.read())
-            hsh = type('')(m.hexdigest())
+            hsh = str(m.hexdigest())
             buf = BytesIO()
             with tarfile.TarFile(fileobj=buf, mode='w') as tf:
                 for dic in dics:
diff --git a/setup/install.py b/setup/install.py
index b4b39df7e6..b21f11b34e 100644
--- a/setup/install.py
+++ b/setup/install.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 # License: GPLv3 Copyright: 2009, Kovid Goyal <kovid at kovidgoyal.net>
 
 
@@ -163,7 +162,7 @@ class Develop(Command):
         try:
             if not os.path.exists(libdir):
                 os.makedirs(libdir)
-        except EnvironmentError:
+        except OSError:
             self.warn('Cannot install calibre environment module to: '+libdir)
         else:
             path = os.path.join(libdir, 'init_calibre.py')
@@ -367,7 +366,7 @@ class Bootstrap(Command):
     def pre_sub_commands(self, opts):
         tdir = self.j(self.d(self.SRC), 'translations')
         clone_cmd = [
-            'git', 'clone', 'https://github.com/{}.git'.format(self.TRANSLATIONS_REPO), 'translations']
+            'git', 'clone', f'https://github.com/{self.TRANSLATIONS_REPO}.git', 'translations']
         if opts.ephemeral:
             if os.path.exists(tdir):
                 shutil.rmtree(tdir)
diff --git a/setup/installers.py b/setup/installers.py
index d48d7f61a9..1b32ca5cba 100644
--- a/setup/installers.py
+++ b/setup/installers.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2016, Kovid Goyal <kovid at kovidgoyal.net>
 
 
@@ -86,7 +85,7 @@ def build_single(which='windows', bitness='64', shutdown=True, sign_installers=T
         dest = os.path.join(base, 'dist', x)
         try:
             os.remove(dest)
-        except EnvironmentError:
+        except OSError:
             pass
         os.link(src, dest)
     if shutdown:
@@ -248,9 +247,9 @@ class ExtDev(Command):
         try:
             path = path.format(ext)
             src = os.path.join(ext_dir, os.path.basename(path))
-            subprocess.check_call(['ssh', '-S', control_path, host, 'chmod', '+w', '"{}"'.format(path)])
+            subprocess.check_call(['ssh', '-S', control_path, host, 'chmod', '+w', f'"{path}"'])
             with open(src, 'rb') as f:
-                p = subprocess.Popen(['ssh', '-S', control_path, host, 'cat - > "{}"'.format(path)], stdin=subprocess.PIPE)
+                p = subprocess.Popen(['ssh', '-S', control_path, host, f'cat - > "{path}"'], stdin=subprocess.PIPE)
                 p.communicate(f.read())
             if p.wait() != 0:
                 raise SystemExit(1)
diff --git a/setup/lc_data.py b/setup/lc_data.py
index a843bab3bb..f632db152c 100644
--- a/setup/lc_data.py
+++ b/setup/lc_data.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python3
-# vim:fileencoding=utf-8
 
 
 __license__ = 'GPL v3'
diff --git a/setup/liberation.py b/setup/liberation.py
index 509320bc31..2c30db9474 100644
--- a/setup/liberation.py
+++ b/setup/liberation.py
@@ -1,7 +1,5 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:fdm=marker:ai
 # License: GPLv3 Copyright: 2019, Kovid Goyal <kovid at kovidgoyal.net>
-from __future__ import absolute_import, division, print_function, unicode_literals
 
 import glob
 import os
diff --git a/setup/mathjax.py b/setup/mathjax.py
index 7a8cd467b2..fa81f29181 100644
--- a/setup/mathjax.py
+++ b/setup/mathjax.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:fdm=marker:ai
 
 
 __license__   = 'GPL v3'
diff --git a/setup/parallel_build.py b/setup/parallel_build.py
index c93b799a3c..7c53f0791d 100644
--- a/setup/parallel_build.py
+++ b/setup/parallel_build.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 
 
 __license__ = 'GPL v3'
diff --git a/setup/plugins_mirror.py b/setup/plugins_mirror.py
index 4d14aecab9..ea580e78bf 100644
--- a/setup/plugins_mirror.py
+++ b/setup/plugins_mirror.py
@@ -1,7 +1,5 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2013, Kovid Goyal <kovid at kovidgoyal.net>
-from __future__ import absolute_import, division, print_function, unicode_literals
 
 
 # Imports {{{
@@ -128,7 +126,7 @@ def parse_index(raw=None):  # {{{
 
         thread_id = url_to_plugin_id(url, deprecated)
         if thread_id in seen:
-            raise ValueError('thread_id for %s and %s is the same: %s' % (seen[thread_id], name, thread_id))
+            raise ValueError(f'thread_id for {seen[thread_id]} and {name} is the same: {thread_id}')
         seen[thread_id] = name
         entry = IndexEntry(name, url, donate, history, uninstall, deprecated, thread_id)
         yield entry
@@ -147,7 +145,7 @@ def load_plugins_index():
     try:
         with open(PLUGINS, 'rb') as f:
             raw = f.read()
-    except IOError as err:
+    except OSError as err:
         if err.errno == errno.ENOENT:
             return {}
         raise
@@ -173,13 +171,13 @@ def convert_node(fields, x, names={}, import_data=None):
         return dict(zip(keys, values))
     elif name == 'Call':
         if len(x.args) != 1 and len(x.keywords) != 0:
-            raise TypeError('Unsupported function call for fields: %s' % (fields,))
+            raise TypeError(f'Unsupported function call for fields: {fields}')
         return tuple(map(conv, x.args))[0]
     elif name == 'Name':
         if x.id not in names:
             if import_data is not None and x.id in import_data[0]:
                 return get_import_data(x.id, import_data[0][x.id], *import_data[1:])
-            raise ValueError('Could not find name %s for fields: %s' % (x.id, fields))
+            raise ValueError(f'Could not find name {x.id} for fields: {fields}')
         return names[x.id]
     elif name == 'BinOp':
         if x.right.__class__.__name__ == 'Str':
@@ -188,7 +186,7 @@ def convert_node(fields, x, names={}, import_data=None):
             return x.right.value
     elif name == 'Attribute':
         return conv(getattr(conv(x.value), x.attr))
-    raise TypeError('Unknown datatype %s for fields: %s' % (x, fields))
+    raise TypeError(f'Unknown datatype {x} for fields: {fields}')
 
 
 Alias = namedtuple('Alias', 'name asname')
@@ -221,7 +219,7 @@ def get_import_data(name, mod, zf, names):
                     return convert_node({x}, node.value)
         if is_module_import:
             return module
-        raise ValueError('Failed to find name: %r in module: %r' % (name, mod))
+        raise ValueError(f'Failed to find name: {name!r} in module: {mod!r}')
     else:
         raise ValueError('Failed to find module: %r' % mod)
 
@@ -457,7 +455,7 @@ def fetch_plugins(old_index):
 
 
 def plugin_to_index(plugin, count):
-    title = '<h3><img src="plugin-icon.png"><a href=%s title="Plugin forum thread">%s</a></h3>' % (  # noqa
+    title = '<h3><img src="plugin-icon.png"><a href={} title="Plugin forum thread">{}</a></h3>'.format(  # noqa
         quoteattr(plugin['thread_url']), escape(plugin['name']))
     released = datetime(*tuple(map(int, re.split(r'\D', plugin['last_modified'])))[:6]).strftime('%e %b, %Y').lstrip()
     details = [
@@ -478,12 +476,12 @@ def plugin_to_index(plugin, count):
         block.append('<li>%s</li>' % li)
     block = '<ul>%s</ul>' % ('\n'.join(block))
     downloads = ('\xa0<span class="download-count">[%d total downloads]</span>' % count) if count else ''
-    zipfile = '<div class="end"><a href=%s title="Download plugin" download=%s>Download plugin \u2193</a>%s</div>' % (
+    zipfile = '<div class="end"><a href={} title="Download plugin" download={}>Download plugin \u2193</a>{}</div>'.format(
         quoteattr(plugin['file']), quoteattr(plugin['name'] + '.zip'), downloads)
     desc = plugin['description'] or ''
     if desc:
         desc = '<p>%s</p>' % desc
-    return '%s\n%s\n%s\n%s\n\n' % (title, desc, block, zipfile)
+    return f'{title}\n{desc}\n{block}\n{zipfile}\n\n'
 
 
 def create_index(index, raw_stats):
@@ -526,14 +524,14 @@ h1 { text-align: center }
     try:
         with open('index.html', 'rb') as f:
             oraw = f.read()
-    except EnvironmentError:
+    except OSError:
         oraw = None
     if raw != oraw:
         atomic_write(raw, 'index.html')
 
     def plugin_stats(x):
         name, count = x
-        return '<tr><td>%s</td><td>%s</td></tr>\n' % (escape(name), count)
+        return f'<tr><td>{escape(name)}</td><td>{count}</td></tr>\n'
 
     pstats = list(map(plugin_stats, sorted(stats.items(), reverse=True, key=lambda x:x[1])))
     stats = '''\
@@ -560,7 +558,7 @@ h1 { text-align: center }
     try:
         with open('stats.html', 'rb') as f:
             oraw = f.read()
-    except EnvironmentError:
+    except OSError:
         oraw = None
     if raw != oraw:
         atomic_write(raw, 'stats.html')
@@ -574,7 +572,7 @@ def singleinstance():
     s = _singleinstance = socket.socket(socket.AF_UNIX)
     try:
         s.bind(b'\0calibre-plugins-mirror-singleinstance')
-    except socket.error as err:
+    except OSError as err:
         if getattr(err, 'errno', None) == errno.EADDRINUSE:
             return False
         raise
@@ -590,7 +588,7 @@ def update_stats():
         try:
             with open('stats.json', 'rb') as f:
                 stats = json.load(f)
-        except EnvironmentError as err:
+        except OSError as err:
             if err.errno != errno.ENOENT:
                 raise
         if os.geteuid() != 0:
@@ -688,7 +686,7 @@ def test_parse():  # {{{
     new_entries = tuple(parse_index(raw))
     for i, entry in enumerate(old_entries):
         if entry != new_entries[i]:
-            print('The new entry: %s != %s' % (new_entries[i], entry))
+            print(f'The new entry: {new_entries[i]} != {entry}')
             raise SystemExit(1)
     pool = ThreadPool(processes=20)
     urls = [e.url for e in new_entries]
@@ -705,7 +703,7 @@ def test_parse():  # {{{
                 break
         new_url, aname = parse_plugin_zip_url(raw)
         if new_url != full_url:
-            print('new url (%s): %s != %s for plugin at: %s' % (aname, new_url, full_url, url))
+            print(f'new url ({aname}): {new_url} != {full_url} for plugin at: {url}')
             raise SystemExit(1)
 
 # }}}
diff --git a/setup/publish.py b/setup/publish.py
index 5414c98d96..6856ca8025 100644
--- a/setup/publish.py
+++ b/setup/publish.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__ = 'GPL v3'
@@ -225,7 +224,7 @@ class Manual(Command):
             orig = self.j(self.d(base), r)
             try:
                 sz = os.stat(orig).st_size
-            except EnvironmentError:
+            except OSError:
                 continue
             if sz == os.stat(f).st_size and filecmp._do_cmp(f, orig):
                 os.remove(f)
@@ -260,7 +259,7 @@ class ManPages(Command):
         os.environ['ALL_USER_MANUAL_LANGUAGES'] = ' '.join(languages)
         try:
             os.makedirs(dest)
-        except EnvironmentError:
+        except OSError:
             pass
         jobs = []
         for l in languages:
@@ -268,7 +267,7 @@ class ManPages(Command):
                 [sys.executable, self.j(base, 'build.py'), '--man-pages', l, dest],
                 '\n\n**************** Building translations for: %s' % l)
             )
-        self.info('\tCreating man pages in {} for {} languages...'.format(dest, len(jobs)))
+        self.info(f'\tCreating man pages in {dest} for {len(jobs)} languages...')
         subprocess.check_call(jobs[0].cmd)
         if not parallel_build(jobs[1:], self.info, verbose=False):
             raise SystemExit(1)
@@ -307,4 +306,4 @@ class TagRelease(Command):
         subprocess.check_call(
             'git tag -s v{0} -m "version-{0}"'.format(__version__).split()
         )
-        subprocess.check_call('git push origin v{0}'.format(__version__).split())
+        subprocess.check_call(f'git push origin v{__version__}'.split())
diff --git a/setup/resources.py b/setup/resources.py
index bbc73b185e..ee60669b8c 100644
--- a/setup/resources.py
+++ b/setup/resources.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__   = 'GPL v3'
@@ -16,17 +15,13 @@ from polyglot.builtins import codepoint_to_chr, itervalues, iteritems, only_unic
 
 def get_opts_from_parser(parser):
     def do_opt(opt):
-        for x in opt._long_opts:
-            yield x
-        for x in opt._short_opts:
-            yield x
+        yield from opt._long_opts
+        yield from opt._short_opts
     for o in parser.option_list:
-        for x in do_opt(o):
-            yield x
+        yield from do_opt(o)
     for g in parser.option_groups:
         for o in g.option_list:
-            for x in do_opt(o):
-                yield x
+            yield from do_opt(o)
 
 
 class Kakasi(Command):  # {{{
@@ -145,7 +140,7 @@ class CACerts(Command):  # {{{
         try:
             with open(self.CA_PATH, 'rb') as f:
                 raw = f.read()
-        except EnvironmentError as err:
+        except OSError as err:
             if err.errno != errno.ENOENT:
                 raise
             raw = b''
@@ -298,7 +293,7 @@ class Resources(Command):  # {{{
             except Exception:
                 continue
             src = src.replace('def ' + func.__name__, 'def replace')
-            imports = ['from %s import %s' % (x.__module__, x.__name__) for x in func.imports]
+            imports = [f'from {x.__module__} import {x.__name__}' for x in func.imports]
             if imports:
                 src = '\n'.join(imports) + '\n\n' + src
             function_dict[func.name] = src
diff --git a/setup/revendor.py b/setup/revendor.py
index 3603d2dd0b..b9786639ec 100755
--- a/setup/revendor.py
+++ b/setup/revendor.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPL v3 Copyright: 2019, Eli Schwartz <eschwartz@archlinux.org>
 
 import os
diff --git a/setup/run-calibre-worker.py b/setup/run-calibre-worker.py
index c5f6cd7c52..a048e2a9f4 100644
--- a/setup/run-calibre-worker.py
+++ b/setup/run-calibre-worker.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2016, Kovid Goyal <kovid at kovidgoyal.net>
 
 
diff --git a/setup/test.py b/setup/test.py
index 5225042e61..df04752b91 100644
--- a/setup/test.py
+++ b/setup/test.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2016, Kovid Goyal <kovid at kovidgoyal.net>
 
 
diff --git a/setup/translations.py b/setup/translations.py
index 269a2c24fd..01cbbb656e 100644
--- a/setup/translations.py
+++ b/setup/translations.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__   = 'GPL v3'
@@ -108,7 +107,7 @@ class POT(Command):  # {{{
         for x in sorted(entries, key=lambda x:name_getter(x).lower()):
             name = name_getter(x)
             if name:
-                ans.append(u'msgid "{}"'.format(name))
+                ans.append(f'msgid "{name}"')
                 ans.append('msgstr ""')
                 ans.append('')
         pot = self.pot_header() + '\n\n' + '\n'.join(ans)
@@ -278,7 +277,7 @@ class Translations(POT):  # {{{
             self.cache_dir_created = True
             try:
                 os.mkdir(ans)
-            except EnvironmentError as err:
+            except OSError as err:
                 if err.errno != errno.EEXIST:
                     raise
         return ans
@@ -293,7 +292,7 @@ class Translations(POT):  # {{{
             with open(self.j(self.cache_dir, cname), 'rb') as f:
                 data = f.read()
                 return data[:20], data[20:]
-        except EnvironmentError as err:
+        except OSError as err:
             if err.errno != errno.ENOENT:
                 raise
         return None, None
@@ -387,7 +386,7 @@ class Translations(POT):  # {{{
                             self.bad.add(msgstr)
                             return match.group()
                         self.seen.add(self.msgid)
-                        return 'msgstr "{}"'.format(self.msgid)
+                        return f'msgstr "{self.msgid}"'
                     self.seen.add(msgstr)
                 return match.group()
 
@@ -405,7 +404,7 @@ class Translations(POT):  # {{{
                 if msgstr:
                     if msgstr and msgstr in self.bad:
                         self.bad.discard(msgstr)
-                        return 'msgstr "{}"'.format(self.msgid)
+                        return f'msgstr "{self.msgid}"'
                 return match.group()
 
         for (po_path, mo_path) in files:
@@ -475,7 +474,7 @@ class Translations(POT):  # {{{
         base = self.d(dest)
         try:
             os.mkdir(base)
-        except EnvironmentError as err:
+        except OSError as err:
             if err.errno != errno.EEXIST:
                 raise
         from calibre.utils.serialize import msgpack_dumps
@@ -506,12 +505,12 @@ class Translations(POT):  # {{{
                     po_data = data.decode('utf-8')
                     data = json.loads(msgfmt(po_data))
                     translated_entries = {k:v for k, v in iteritems(data['entries']) if v and sum(map(len, v))}
-                    data[u'entries'] = translated_entries
-                    data[u'hash'] = h.hexdigest()
+                    data['entries'] = translated_entries
+                    data['hash'] = h.hexdigest()
                     cdata = b'{}'
                     if translated_entries:
                         raw = json.dumps(data, ensure_ascii=False, sort_keys=True)
-                        if isinstance(raw, type(u'')):
+                        if isinstance(raw, str):
                             raw = raw.encode('utf-8')
                         cdata = raw
                     self.write_cache(cdata, current_hash, src)
@@ -539,7 +538,7 @@ class Translations(POT):  # {{{
                     cm = langnames_to_langcodes([omsgid, msgid])
                     if cm[msgid] and cm[omsgid] and cm[msgid] != cm[omsgid]:
                         has_errors = True
-                        self.iso639_errors.append('In file %s the name %s is used as translation for both %s and %s' % (
+                        self.iso639_errors.append('In file {} the name {} is used as translation for both {} and {}'.format(
                             os.path.basename(path), msgstr, msgid, rmap[msgstr]))
                     # raise SystemExit(1)
                 rmap[msgstr] = msgid
@@ -730,8 +729,8 @@ class GetTranslations(Translations):  # {{{
                 if changed:
                     f.save()
         for slug, languages in iteritems(changes):
-            print('Pushing fixes for languages: %s in %s' % (', '.join(languages), slug))
-            self.tx('push -r calibre.%s -t -l %s' % (slug, ','.join(languages)))
+            print('Pushing fixes for languages: {} in {}'.format(', '.join(languages), slug))
+            self.tx('push -r calibre.{} -t -l {}'.format(slug, ','.join(languages)))
 
     def check_for_errors(self):
         self.info('Checking for errors in .po files...')
@@ -750,8 +749,8 @@ class GetTranslations(Translations):  # {{{
                 languages.add(os.path.basename(parts[-1]).partition('.')[0])
         if languages:
             pot = 'main' if group == 'calibre' else group.replace('-', '_')
-            print('Pushing fixes for %s.pot languages: %s' % (pot, ', '.join(languages)))
-            self.tx('push -r calibre.{} -t -l '.format(pot) + ','.join(languages))
+            print('Pushing fixes for {}.pot languages: {}'.format(pot, ', '.join(languages)))
+            self.tx(f'push -r calibre.{pot} -t -l ' + ','.join(languages))
 
     def check_group(self, group):
         files = glob.glob(os.path.join(self.TRANSLATIONS, group, '*.po'))
@@ -769,11 +768,11 @@ class GetTranslations(Translations):  # {{{
         def check_for_control_chars(f):
             with open(f, 'rb') as f:
                 raw = f.read().decode('utf-8')
-            pat = re.compile(type(u'')(r'[\0-\x08\x0b\x0c\x0e-\x1f\x7f\x80-\x9f]'))
+            pat = re.compile(r'[\0-\x08\x0b\x0c\x0e-\x1f\x7f\x80-\x9f]')
             errs = []
             for i, line in enumerate(raw.splitlines()):
                 if pat.search(line) is not None:
-                    errs.append('There are ASCII control codes on line number: {}'.format(i + 1))
+                    errs.append(f'There are ASCII control codes on line number: {i + 1}')
             return '\n'.join(errs)
 
         for f in files:
@@ -848,7 +847,7 @@ class ISO639(Command):  # {{{
         m3to2 = {}
         nm = {}
         codes2, codes3 = set(), set()
-        unicode_type = type(u'')
+        unicode_type = str
         for x in entries:
             two = x.get('alpha_2')
             if two:
@@ -874,9 +873,9 @@ class ISO639(Command):  # {{{
             base_name = name.lower()
             nm[base_name] = threeb
 
-        x = {u'by_2':by_2, u'by_3':by_3, u'codes2':codes2,
-                u'codes3':codes3, u'2to3':m2to3,
-                u'3to2':m3to2, u'name_map':nm}
+        x = {'by_2':by_2, 'by_3':by_3, 'codes2':codes2,
+                'codes3':codes3, '2to3':m2to3,
+                '3to2':m3to2, 'name_map':nm}
         from calibre.utils.serialize import msgpack_dumps
         with open(dest, 'wb') as f:
             f.write(msgpack_dumps(x))
@@ -911,7 +910,7 @@ class ISO3166(ISO639):  # {{{
         codes = set()
         three_map = {}
         name_map = {}
-        unicode_type = type(u'')
+        unicode_type = str
         for x in db['3166-1']:
             two = x.get('alpha_2')
             if two:
@@ -923,7 +922,7 @@ class ISO3166(ISO639):  # {{{
             three = x.get('alpha_3')
             if three:
                 three_map[unicode_type(three)] = two
-        x = {u'names':name_map, u'codes':frozenset(codes), u'three_map':three_map}
+        x = {'names':name_map, 'codes':frozenset(codes), 'three_map':three_map}
         from calibre.utils.serialize import msgpack_dumps
         with open(dest, 'wb') as f:
             f.write(msgpack_dumps(x))
diff --git a/setup/unix-ci.py b/setup/unix-ci.py
index 64e307a952..de4c21bc86 100644
--- a/setup/unix-ci.py
+++ b/setup/unix-ci.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2017, Kovid Goyal <kovid at kovidgoyal.net>
 
 
@@ -119,7 +118,7 @@ def main():
 
         tball = 'macos-64' if ismacos else 'linux-64'
         download_and_decompress(
-            'https://download.calibre-ebook.com/ci/calibre3/{}.tar.xz'.format(tball), SW
+            f'https://download.calibre-ebook.com/ci/calibre3/{tball}.tar.xz', SW
         )
         if not ismacos:
             install_linux_deps()
@@ -152,7 +151,7 @@ username = api
         run_python('setup.py test')
         run_python('setup.py test_rs')
     else:
-        raise SystemExit('Unknown action: {}'.format(action))
+        raise SystemExit(f'Unknown action: {action}')
 
 
 if __name__ == '__main__':
diff --git a/setup/upload.py b/setup/upload.py
index 27d596bab9..1d3ce58b13 100644
--- a/setup/upload.py
+++ b/setup/upload.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=UTF-8:ts=4:sw=4:sta:et:sts=4:ai
 
 
 __license__   = 'GPL v3'
@@ -34,9 +33,9 @@ def installers(include_source=True):
     installers.append(installer_name('txz', is64bit=True))
     installers.append(installer_name('msi', is64bit=True))
     if include_source:
-        installers.insert(0, 'dist/%s-%s.tar.xz' % (__appname__, __version__))
+        installers.insert(0, f'dist/{__appname__}-{__version__}.tar.xz')
     installers.append(
-        'dist/%s-portable-installer-%s.exe' % (__appname__, __version__)
+        f'dist/{__appname__}-portable-installer-{__version__}.exe'
     )
     return installers
 
@@ -126,7 +125,7 @@ def get_fosshub_data():
 def send_data(loc):
     subprocess.check_call([
         'rsync', '--inplace', '--delete', '-r', '-zz', '-h', '--info=progress2', '-e',
-        'ssh -x', loc + '/', '%s@%s:%s' % (STAGING_USER, STAGING_HOST, STAGING_DIR)
+        'ssh -x', loc + '/', f'{STAGING_USER}@{STAGING_HOST}:{STAGING_DIR}'
     ])
 
 
@@ -160,7 +159,7 @@ def calibre_cmdline(ver):
 def run_remote_upload(args):
     print('Running remotely:', ' '.join(args))
     subprocess.check_call([
-        'ssh', '-x', '%s@%s' % (STAGING_USER, STAGING_HOST), 'cd', STAGING_DIR, '&&',
+        'ssh', '-x', f'{STAGING_USER}@{STAGING_HOST}', 'cd', STAGING_DIR, '&&',
         'python', 'hosting.py'
     ] + args)
 
@@ -185,7 +184,7 @@ def upload_to_fosshub():
         if ans.get('error'):
             raise SystemExit(ans['error'])
         if res.getcode() != 200:
-            raise SystemExit('Request to {} failed with response code: {}'.format(path, res.getcode()))
+            raise SystemExit(f'Request to {path} failed with response code: {res.getcode()}')
         # from pprint import pprint
         # pprint(ans)
         return ans['status'] if 'status' in ans else ans['data']
@@ -204,7 +203,7 @@ def upload_to_fosshub():
     entries = []
     for fname in files:
         desc = installer_description(fname)
-        url = 'https://download.calibre-ebook.com/%s/%s' % (
+        url = 'https://download.calibre-ebook.com/{}/{}'.format(
             __version__, os.path.basename(fname)
         )
         entries.append({
@@ -221,7 +220,7 @@ def upload_to_fosshub():
     data = json.dumps(jq)
     # print(data)
     data = data.encode('utf-8')
-    if not request('projects/{}/releases/'.format(project_id), data=data):
+    if not request(f'projects/{project_id}/releases/', data=data):
         raise SystemExit('Failed to queue publish job with fosshub')
 
 
@@ -263,7 +262,7 @@ class UploadInstallers(Command):  # {{{
     def record_sizes(self, sizes):
         print('\nRecording dist sizes')
         args = [
-            '%s:%s:%s' % (__version__, fname, size)
+            f'{__version__}:{fname}:{size}'
             for fname, size in iteritems(sizes)
         ]
         check_call(['ssh', 'code', '/usr/local/bin/dist_sizes'] + args)
@@ -285,7 +284,7 @@ class UploadInstallers(Command):  # {{{
 
         with open(os.path.join(tdir, 'fmap'), 'wb') as fo:
             for f, desc in iteritems(files):
-                fo.write(('%s: %s\n' % (f, desc)).encode('utf-8'))
+                fo.write((f'{f}: {desc}\n').encode())
 
         while True:
             try:
@@ -345,7 +344,7 @@ class UploadUserManual(Command):  # {{{
                             for y in os.listdir(x):
                                 zf.write(os.path.join(x, y))
             bname = self.b(path) + '_plugin.zip'
-            dest = '%s/%s' % (DOWNLOADS, bname)
+            dest = f'{DOWNLOADS}/{bname}'
             subprocess.check_call(['scp', f.name, 'main:' + dest])
 
     def run(self, opts):
@@ -387,7 +386,7 @@ class UploadDemo(Command):  # {{{
             shell=True
         )
 
-        check_call('scp /tmp/html-demo.zip main:%s/' % (DOWNLOADS, ), shell=True)
+        check_call(f'scp /tmp/html-demo.zip main:{DOWNLOADS}/', shell=True)
 
 
 # }}}
diff --git a/setup/vcvars.py b/setup/vcvars.py
index 90f2c32e2d..7fc61ad880 100644
--- a/setup/vcvars.py
+++ b/setup/vcvars.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2016, Kovid Goyal <kovid at kovidgoyal.net>
 
 import ctypes.wintypes
@@ -129,7 +128,7 @@ def query_process(cmd, is64bit):
 def query_vcvarsall(is64bit=True):
     plat = 'amd64' if is64bit else 'amd64_x86'
     vcvarsall = find_vcvarsall()
-    env = query_process('"%s" %s & set' % (vcvarsall, plat), is64bit)
+    env = query_process(f'"{vcvarsall}" {plat} & set', is64bit)
 
     def g(k):
         try:
diff --git a/setup/win-ci.py b/setup/win-ci.py
index 076bac12bc..15557ae36e 100644
--- a/setup/win-ci.py
+++ b/setup/win-ci.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python
-# vim:fileencoding=utf-8
 # License: GPLv3 Copyright: 2016, Kovid Goyal <kovid at kovidgoyal.net>