diff --git a/src/calibre/gui2/actions/copy_to_library.py b/src/calibre/gui2/actions/copy_to_library.py
index 5a626dac42..87990e43ae 100644
--- a/src/calibre/gui2/actions/copy_to_library.py
+++ b/src/calibre/gui2/actions/copy_to_library.py
@@ -15,7 +15,7 @@ from collections import defaultdict
 from PyQt5.Qt import (
     QToolButton, QDialog, QGridLayout, QIcon, QLabel, QDialogButtonBox,
     QApplication, QLineEdit, QHBoxLayout, QFormLayout, QCheckBox, QWidget,
-    QScrollArea, QVBoxLayout, Qt, QListWidgetItem, QListWidget, QSize)
+    QScrollArea, QVBoxLayout, Qt, QListWidgetItem, QListWidget, QSize, QAbstractItemView)
 
 from calibre import as_unicode
 from calibre.constants import ismacos
@@ -207,7 +207,7 @@ class ChooseLibrary(Dialog):  # {{{
     def setup_ui(self):
         self.l = l = QGridLayout(self)
         self.items = i = QListWidget(self)
-        i.setSelectionMode(i.SingleSelection)
+        i.setSelectionMode(QAbstractItemView.SelectionMode.SingleSelection)
         i.currentItemChanged.connect(self.current_changed)
         l.addWidget(i)
         self.v = v = QVBoxLayout()
diff --git a/src/calibre/gui2/complete2.py b/src/calibre/gui2/complete2.py
index 864457c219..b4f61a1b7e 100644
--- a/src/calibre/gui2/complete2.py
+++ b/src/calibre/gui2/complete2.py
@@ -7,7 +7,7 @@ __copyright__ = '2012, Kovid Goyal <kovid@kovidgoyal.net>'
 __docformat__ = 'restructuredtext en'
 
 from PyQt5.Qt import (
-    QLineEdit, QAbstractListModel, Qt, pyqtSignal, QObject, QKeySequence,
+    QLineEdit, QAbstractListModel, Qt, pyqtSignal, QObject, QKeySequence, QAbstractItemView,
     QApplication, QListView, QPoint, QModelIndex,
     QStyleOptionComboBox, QStyle, QComboBox, QTimer)
 try:
@@ -93,7 +93,7 @@ class Completer(QListView):  # {{{
         self.setEditTriggers(self.NoEditTriggers)
         self.setHorizontalScrollBarPolicy(Qt.ScrollBarPolicy.ScrollBarAlwaysOff)
         self.setSelectionBehavior(self.SelectRows)
-        self.setSelectionMode(self.SingleSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.SingleSelection)
         self.setUniformItemSizes(True)
         self.setAlternatingRowColors(True)
         self.setModel(CompleteModel(self, sort_func=sort_func, strip_completion_entries=strip_completion_entries))
diff --git a/src/calibre/gui2/dialogs/authors_edit.py b/src/calibre/gui2/dialogs/authors_edit.py
index b5dcc4844f..c554986a7f 100644
--- a/src/calibre/gui2/dialogs/authors_edit.py
+++ b/src/calibre/gui2/dialogs/authors_edit.py
@@ -9,7 +9,7 @@ from collections import OrderedDict
 
 from PyQt5.Qt import (
     QDialog, QGridLayout, QDialogButtonBox, QListWidget, QApplication, Qt,
-    pyqtSignal, QSize, QPushButton, QIcon, QStyledItemDelegate, QLabel)
+    pyqtSignal, QSize, QPushButton, QIcon, QStyledItemDelegate, QLabel, QAbstractItemView)
 
 from calibre.utils.config_base import tweaks
 from calibre.gui2 import gprefs
@@ -51,7 +51,7 @@ class List(QListWidget):
     def __init__(self, all_authors, parent):
         QListWidget.__init__(self, parent)
         self.setDragEnabled(True)
-        self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.setDropIndicatorShown(True)
         self.setDragDropMode(self.InternalMove)
         self.setAlternatingRowColors(True)
diff --git a/src/calibre/gui2/dialogs/exim.py b/src/calibre/gui2/dialogs/exim.py
index 8e86336d65..ad1f85dee6 100644
--- a/src/calibre/gui2/dialogs/exim.py
+++ b/src/calibre/gui2/dialogs/exim.py
@@ -10,7 +10,7 @@ import os, stat
 from PyQt5.Qt import (
     QSize, QStackedLayout, QWidget, QVBoxLayout, QLabel, QPushButton,
     QListWidget, QListWidgetItem, QIcon, Qt, pyqtSignal, QGridLayout,
-    QProgressBar, QDialog, QDialogButtonBox, QScrollArea, QLineEdit, QFrame
+    QProgressBar, QDialog, QDialogButtonBox, QScrollArea, QLineEdit, QFrame, QAbstractItemView
 )
 
 from calibre import human_readable, as_unicode
@@ -200,7 +200,7 @@ class EximDialog(Dialog):
         la.setWordWrap(True), l.addWidget(la)
         self.lib_list = ll = QListWidget(self)
         l.addWidget(ll)
-        ll.setSelectionMode(ll.ExtendedSelection)
+        ll.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         ll.setStyleSheet('QListView::item { padding: 5px }')
         ll.setAlternatingRowColors(True)
         lpaths = all_known_libraries()
diff --git a/src/calibre/gui2/dialogs/select_formats.py b/src/calibre/gui2/dialogs/select_formats.py
index d11ec3f6b1..8c5571903d 100644
--- a/src/calibre/gui2/dialogs/select_formats.py
+++ b/src/calibre/gui2/dialogs/select_formats.py
@@ -8,7 +8,7 @@ __docformat__ = 'restructuredtext en'
 
 
 from PyQt5.Qt import QVBoxLayout, QDialog, QLabel, QDialogButtonBox, Qt, \
-        QAbstractListModel, QListView, QSize, QApplication
+        QAbstractListModel, QListView, QSize, QApplication, QAbstractItemView
 
 from calibre.gui2 import file_icon_provider
 
@@ -70,8 +70,8 @@ class SelectFormats(QDialog):
             self.fview.setStyleSheet('QListView { %s }' % sheet)
         self._l.addWidget(self.fview)
         self.fview.setModel(self.formats)
-        self.fview.setSelectionMode(self.fview.SingleSelection if single else
-                self.fview.MultiSelection)
+        self.fview.setSelectionMode(QAbstractItemView.SelectionMode.SingleSelection if single else
+                QAbstractItemView.SelectionMode.MultiSelection)
         self.bbox = \
         QDialogButtonBox(QDialogButtonBox.StandardButton.Ok|QDialogButtonBox.StandardButton.Cancel,
                 Qt.Orientation.Horizontal, self)
diff --git a/src/calibre/gui2/font_family_chooser.py b/src/calibre/gui2/font_family_chooser.py
index 3a8f677546..b60b95b9be 100644
--- a/src/calibre/gui2/font_family_chooser.py
+++ b/src/calibre/gui2/font_family_chooser.py
@@ -12,7 +12,7 @@ from PyQt5.Qt import (QFontInfo, QFontMetrics, Qt, QFont, QFontDatabase, QPen,
         QStyledItemDelegate, QSize, QStyle, QStringListModel, pyqtSignal,
         QDialog, QVBoxLayout, QApplication, QFontComboBox, QPushButton,
         QToolButton, QGridLayout, QListView, QWidget, QDialogButtonBox, QIcon,
-        QHBoxLayout, QLabel, QLineEdit, QSizePolicy)
+        QHBoxLayout, QLabel, QLineEdit, QSizePolicy, QAbstractItemView)
 
 from calibre.constants import config_dir
 from calibre.gui2 import choose_files, error_dialog, info_dialog, empty_index
@@ -186,7 +186,7 @@ class FontsView(QListView):
 
     def __init__(self, parent):
         QListView.__init__(self, parent)
-        self.setSelectionMode(self.SingleSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.SingleSelection)
         self.setAlternatingRowColors(True)
         self.d = FontFamilyDelegate(self)
         self.setItemDelegate(self.d)
diff --git a/src/calibre/gui2/icon_theme.py b/src/calibre/gui2/icon_theme.py
index c5ff372a9e..b510c7527f 100644
--- a/src/calibre/gui2/icon_theme.py
+++ b/src/calibre/gui2/icon_theme.py
@@ -16,7 +16,7 @@ from PyQt5.Qt import (
     QLineEdit, QSpinBox, QTextEdit, QSize, QListWidgetItem, QIcon, QImage,
     pyqtSignal, QStackedLayout, QWidget, QLabel, Qt, QComboBox, QPixmap,
     QGridLayout, QStyledItemDelegate, QApplication, QStaticText,
-    QStyle, QPen, QProgressDialog
+    QStyle, QPen, QProgressDialog, QAbstractItemView
 )
 try:
     from PyQt5 import sip
@@ -217,7 +217,7 @@ class ThemeCreateDialog(Dialog):
         l.setFieldGrowthPolicy(l.ExpandingFieldsGrow)
         self.missing_icons_group = mg = QGroupBox(self)
         self.mising_icons = mi = QListWidget(mg)
-        mi.setSelectionMode(mi.NoSelection)
+        mi.setSelectionMode(QAbstractItemView.SelectionMode.NoSelection)
         mg.l = QVBoxLayout(mg)
         mg.l.addWidget(mi)
         self.splitter.addWidget(mg)
diff --git a/src/calibre/gui2/library/alternate_views.py b/src/calibre/gui2/library/alternate_views.py
index 39b33deae1..4b7ebbd0e9 100644
--- a/src/calibre/gui2/library/alternate_views.py
+++ b/src/calibre/gui2/library/alternate_views.py
@@ -704,7 +704,7 @@ class GridView(QListView):
         # restore_vpos()
         # self.setLayoutMode(self.Batched)
         self.setResizeMode(self.Adjust)
-        self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.setVerticalScrollMode(self.ScrollPerPixel)
         self.delegate = CoverDelegate(self)
         self.delegate.animation.valueChanged.connect(self.animation_value_changed)
diff --git a/src/calibre/gui2/library/annotations.py b/src/calibre/gui2/library/annotations.py
index 6bfa04255b..48b2a150e5 100644
--- a/src/calibre/gui2/library/annotations.py
+++ b/src/calibre/gui2/library/annotations.py
@@ -10,7 +10,7 @@ from PyQt5.Qt import (
     QApplication, QCheckBox, QComboBox, QCursor, QDateTime, QFont, QFormLayout,
     QHBoxLayout, QIcon, QKeySequence, QLabel, QMenu, QPalette, QPlainTextEdit, QSize,
     QSplitter, Qt, QTextBrowser, QTimer, QToolButton, QTreeWidget, QTreeWidgetItem,
-    QVBoxLayout, QWidget, pyqtSignal
+    QVBoxLayout, QWidget, pyqtSignal, QAbstractItemView
 )
 
 from calibre import prepare_string_for_xml
@@ -204,7 +204,7 @@ class ResultsList(QTreeWidget):
     def __init__(self, parent):
         QTreeWidget.__init__(self, parent)
         self.setHeaderHidden(True)
-        self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.setContextMenuPolicy(Qt.ContextMenuPolicy.CustomContextMenu)
         self.customContextMenuRequested.connect(self.show_context_menu)
         self.delegate = AnnotsResultsDelegate(self)
diff --git a/src/calibre/gui2/metadata/pdf_covers.py b/src/calibre/gui2/metadata/pdf_covers.py
index 8716e610ec..cf87882494 100644
--- a/src/calibre/gui2/metadata/pdf_covers.py
+++ b/src/calibre/gui2/metadata/pdf_covers.py
@@ -11,7 +11,7 @@ from threading import Thread
 from glob import glob
 
 from PyQt5.Qt import (
-    QDialog, QApplication, QLabel, QVBoxLayout, QDialogButtonBox, Qt,
+    QDialog, QApplication, QLabel, QVBoxLayout, QDialogButtonBox, Qt, QAbstractItemView,
     pyqtSignal, QListWidget, QListWidgetItem, QSize, QPixmap, QStyledItemDelegate
 )
 try:
@@ -59,7 +59,7 @@ class PDFCovers(QDialog):
         self.item_delegate = CoverDelegate(self)
         c.setItemDelegate(self.item_delegate)
         c.setIconSize(QSize(120, 160))
-        c.setSelectionMode(c.SingleSelection)
+        c.setSelectionMode(QAbstractItemView.SelectionMode.SingleSelection)
         c.setViewMode(c.IconMode)
         c.setUniformItemSizes(True)
         c.setResizeMode(c.Adjust)
diff --git a/src/calibre/gui2/metadata/single_download.py b/src/calibre/gui2/metadata/single_download.py
index c80eeb24e1..df6126f984 100644
--- a/src/calibre/gui2/metadata/single_download.py
+++ b/src/calibre/gui2/metadata/single_download.py
@@ -20,7 +20,7 @@ from PyQt5.Qt import (
     QWidget, QTableView, QGridLayout, QPalette, QTimer, pyqtSignal,
     QAbstractTableModel, QSize, QListView, QPixmap, QModelIndex,
     QAbstractListModel, QRect, QTextBrowser, QStringListModel, QMenu,
-    QCursor, QHBoxLayout, QPushButton, QSizePolicy, QSplitter)
+    QCursor, QHBoxLayout, QPushButton, QSizePolicy, QSplitter, QAbstractItemView)
 
 from calibre.customize.ui import metadata_plugins
 from calibre.ebooks.metadata import authors_to_string, rating_to_stars
@@ -214,7 +214,7 @@ class ResultsView(QTableView):  # {{{
     def __init__(self, parent=None):
         QTableView.__init__(self, parent)
         self.rt_delegate = RichTextDelegate(self)
-        self.setSelectionMode(self.SingleSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.SingleSelection)
         self.setAlternatingRowColors(True)
         self.setSelectionBehavior(self.SelectRows)
         self.setIconSize(QSize(24, 24))
@@ -774,7 +774,7 @@ class CoversView(QListView):  # {{{
         self.setResizeMode(self.Adjust)
         self.setGridSize(QSize(190, 260))
         self.setIconSize(QSize(*CoverDelegate.ICON_SIZE))
-        self.setSelectionMode(self.SingleSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.SingleSelection)
         self.setViewMode(self.IconMode)
 
         self.delegate = CoverDelegate(self)
diff --git a/src/calibre/gui2/preferences/coloring.py b/src/calibre/gui2/preferences/coloring.py
index cc0003e18f..4ba2cba1c6 100644
--- a/src/calibre/gui2/preferences/coloring.py
+++ b/src/calibre/gui2/preferences/coloring.py
@@ -12,7 +12,7 @@ from PyQt5.Qt import (QWidget, QDialog, QLabel, QGridLayout, QComboBox, QSize,
         QLineEdit, QIntValidator, QDoubleValidator, QFrame, Qt, QIcon, QHBoxLayout,
         QScrollArea, QPushButton, QVBoxLayout, QDialogButtonBox, QToolButton,
         QListView, QAbstractListModel, pyqtSignal, QSizePolicy, QSpacerItem,
-        QApplication, QStandardItem, QStandardItemModel, QCheckBox, QMenu)
+        QApplication, QStandardItem, QStandardItemModel, QCheckBox, QMenu, QAbstractItemView)
 
 from calibre import prepare_string_for_xml, sanitize_file_name, as_unicode
 from calibre.constants import config_dir
@@ -911,7 +911,7 @@ class EditRules(QWidget):  # {{{
         self.g = g = QGridLayout()
         self.rules_view = QListView(self)
         self.rules_view.doubleClicked.connect(self.edit_rule)
-        self.rules_view.setSelectionMode(self.rules_view.ExtendedSelection)
+        self.rules_view.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.rules_view.setAlternatingRowColors(True)
         self.rtfd = RichTextDelegate(parent=self.rules_view, max_width=400)
         self.rules_view.setItemDelegate(self.rtfd)
diff --git a/src/calibre/gui2/preferences/texture_chooser.py b/src/calibre/gui2/preferences/texture_chooser.py
index 402a9f1234..aea5da7f47 100644
--- a/src/calibre/gui2/preferences/texture_chooser.py
+++ b/src/calibre/gui2/preferences/texture_chooser.py
@@ -9,7 +9,7 @@ import glob, os, shutil
 from functools import partial
 from PyQt5.Qt import (
     QDialog, QVBoxLayout, QListWidget, QListWidgetItem, Qt, QIcon,
-    QApplication, QSize, QDialogButtonBox, QTimer, QLabel)
+    QApplication, QSize, QDialogButtonBox, QTimer, QLabel, QAbstractItemView)
 
 from calibre.constants import config_dir
 from calibre.gui2 import choose_files, error_dialog
@@ -49,7 +49,7 @@ class TextureChooser(QDialog):
         il.setViewMode(il.IconMode)
         il.setFlow(il.LeftToRight)
         il.setSpacing(20)
-        il.setSelectionMode(il.SingleSelection)
+        il.setSelectionMode(QAbstractItemView.SelectionMode.SingleSelection)
         il.itemSelectionChanged.connect(self.update_remove_state)
         l.addWidget(il)
 
diff --git a/src/calibre/gui2/search_restriction_mixin.py b/src/calibre/gui2/search_restriction_mixin.py
index 8ae7234eba..2b144cccc8 100644
--- a/src/calibre/gui2/search_restriction_mixin.py
+++ b/src/calibre/gui2/search_restriction_mixin.py
@@ -9,7 +9,7 @@ from functools import partial
 
 from PyQt5.Qt import (
     Qt, QMenu, QIcon, QDialog, QGridLayout, QLabel, QLineEdit, QComboBox,
-    QDialogButtonBox, QSize, QVBoxLayout, QListWidget, QRadioButton, QAction, QTextBrowser)
+    QDialogButtonBox, QSize, QVBoxLayout, QListWidget, QRadioButton, QAction, QTextBrowser, QAbstractItemView)
 
 from calibre.gui2 import error_dialog, question_dialog, gprefs
 from calibre.gui2.dialogs.confirm_delete import confirm
@@ -32,7 +32,7 @@ class SelectNames(QDialog):  # {{{
 
         self._names = QListWidget(self)
         self._names.addItems(sorted(names, key=sort_key))
-        self._names.setSelectionMode(self._names.MultiSelection)
+        self._names.setSelectionMode(QAbstractItemView.SelectionMode.MultiSelection)
         l.addWidget(self._names)
 
         self._or = QRadioButton(_('Match any of the selected %s')%txt)
diff --git a/src/calibre/gui2/tag_mapper.py b/src/calibre/gui2/tag_mapper.py
index 254c04e8d9..fcf6dc6c84 100644
--- a/src/calibre/gui2/tag_mapper.py
+++ b/src/calibre/gui2/tag_mapper.py
@@ -8,7 +8,7 @@ import textwrap
 
 from PyQt5.Qt import (
     QWidget, QVBoxLayout, QHBoxLayout, QPushButton, QLabel, QListWidget, QIcon,
-    QSize, QComboBox, QLineEdit, QListWidgetItem, QStyledItemDelegate,
+    QSize, QComboBox, QLineEdit, QListWidgetItem, QStyledItemDelegate, QAbstractItemView,
     QStaticText, Qt, QStyle, QToolButton, QInputDialog, QMenu, pyqtSignal
 )
 
@@ -295,7 +295,7 @@ class Rules(QWidget):
         l.addLayout(h)
         self.rule_list = r = QListWidget(self)
         self.delegate = Delegate(self)
-        r.setSelectionMode(r.ExtendedSelection)
+        r.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         r.setItemDelegate(self.delegate)
         r.doubleClicked.connect(self.edit_rule)
         h.addWidget(r)
diff --git a/src/calibre/gui2/toc/main.py b/src/calibre/gui2/toc/main.py
index 668b4b5ab3..1b04c8775b 100644
--- a/src/calibre/gui2/toc/main.py
+++ b/src/calibre/gui2/toc/main.py
@@ -10,7 +10,7 @@ from functools import partial
 from PyQt5.Qt import (
     QApplication, QCheckBox, QCursor, QDialog, QDialogButtonBox, QFrame, QGridLayout,
     QIcon, QInputDialog, QItemSelectionModel, QKeySequence, QLabel, QMenu,
-    QPushButton, QScrollArea, QSize, QSizePolicy, QStackedWidget, Qt,
+    QPushButton, QScrollArea, QSize, QSizePolicy, QStackedWidget, Qt, QAbstractItemView,
     QToolButton, QTreeWidget, QTreeWidgetItem, QVBoxLayout, QWidget, pyqtSignal
 )
 from threading import Thread
@@ -386,7 +386,7 @@ class TreeWidget(QTreeWidget):  # {{{
         self.setHeaderLabel(_('Table of Contents'))
         self.setIconSize(QSize(ICON_SIZE, ICON_SIZE))
         self.setDragEnabled(True)
-        self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.viewport().setAcceptDrops(True)
         self.setDropIndicatorShown(True)
         self.setDragDropMode(self.InternalMove)
diff --git a/src/calibre/gui2/tweak_book/char_select.py b/src/calibre/gui2/tweak_book/char_select.py
index e2ec301d76..d0f8bb12b5 100644
--- a/src/calibre/gui2/tweak_book/char_select.py
+++ b/src/calibre/gui2/tweak_book/char_select.py
@@ -13,7 +13,7 @@ from PyQt5.Qt import (
     QAbstractItemModel, QAbstractListModel, QApplication, QCheckBox, QGridLayout,
     QHBoxLayout, QIcon, QInputMethodEvent, QLabel, QListView, QMenu, QMimeData,
     QModelIndex, QPen, QPushButton, QSize, QSizePolicy, QSplitter,
-    QStyledItemDelegate, Qt, QToolButton, QTreeView, pyqtSignal
+    QStyledItemDelegate, Qt, QToolButton, QTreeView, pyqtSignal, QAbstractItemView
 )
 
 from calibre.gui2.tweak_book import tprefs
@@ -618,7 +618,7 @@ class CharView(QListView):
             self.setDropIndicatorShown(True)
             self._model.allow_dnd = False
         else:
-            self.setSelectionMode(self.ExtendedSelection)
+            self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
             self.viewport().setAcceptDrops(True)
             self.setDragEnabled(True)
             self.setAcceptDrops(True)
diff --git a/src/calibre/gui2/tweak_book/check.py b/src/calibre/gui2/tweak_book/check.py
index f08dc45358..666ef8438b 100644
--- a/src/calibre/gui2/tweak_book/check.py
+++ b/src/calibre/gui2/tweak_book/check.py
@@ -9,7 +9,8 @@ import sys
 
 from PyQt5.Qt import (
      QIcon, Qt, QSplitter, QListWidget, QTextBrowser, QPalette, QMenu,
-     QListWidgetItem, pyqtSignal, QApplication, QStyledItemDelegate)
+     QListWidgetItem, pyqtSignal, QApplication, QStyledItemDelegate,
+     QAbstractItemView)
 
 from calibre.ebooks.oeb.polish.check.base import WARN, INFO, DEBUG, ERROR, CRITICAL
 from calibre.ebooks.oeb.polish.check.main import run_checks, fix_errors
@@ -70,7 +71,7 @@ class Check(QSplitter):
         self.items.setSpacing(3)
         self.items.itemDoubleClicked.connect(self.current_item_activated)
         self.items.currentItemChanged.connect(self.current_item_changed)
-        self.items.setSelectionMode(self.items.NoSelection)
+        self.items.setSelectionMode(QAbstractItemView.SelectionMode.NoSelection)
         self.delegate = Delegate(self.items)
         self.items.setItemDelegate(self.delegate)
         self.addWidget(i)
diff --git a/src/calibre/gui2/tweak_book/file_list.py b/src/calibre/gui2/tweak_book/file_list.py
index 5bfd630ee3..a2064d9724 100644
--- a/src/calibre/gui2/tweak_book/file_list.py
+++ b/src/calibre/gui2/tweak_book/file_list.py
@@ -11,7 +11,7 @@ from collections import Counter, OrderedDict, defaultdict
 from functools import partial
 from PyQt5.Qt import (
     QApplication, QCheckBox, QDialog, QDialogButtonBox, QFont, QFormLayout,
-    QGridLayout, QIcon, QInputDialog, QLabel, QLineEdit, QListWidget,
+    QGridLayout, QIcon, QInputDialog, QLabel, QLineEdit, QListWidget, QAbstractItemView,
     QListWidgetItem, QMenu, QPainter, QPixmap, QRadioButton, QScrollArea, QSize,
     QSpinBox, QStyle, QStyledItemDelegate, Qt, QTimer, QTreeWidget, QTreeWidgetItem,
     QVBoxLayout, QWidget, pyqtSignal
@@ -252,7 +252,7 @@ class FileList(QTreeWidget, OpenWithHandler):
         self.header().close()
         self.setDragEnabled(True)
         self.setEditTriggers(self.EditKeyPressed)
-        self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.viewport().setAcceptDrops(True)
         self.setDropIndicatorShown(True)
         self.setDragDropMode(self.InternalMove)
diff --git a/src/calibre/gui2/tweak_book/manage_fonts.py b/src/calibre/gui2/tweak_book/manage_fonts.py
index fe5f28b2df..e18732a4ae 100644
--- a/src/calibre/gui2/tweak_book/manage_fonts.py
+++ b/src/calibre/gui2/tweak_book/manage_fonts.py
@@ -11,7 +11,7 @@ from io import BytesIO
 from PyQt5.Qt import (
     QSplitter, QVBoxLayout, QTableView, QWidget, QLabel, QAbstractTableModel,
     Qt, QTimer, QPushButton, pyqtSignal, QFormLayout, QLineEdit, QIcon, QSize,
-    QHBoxLayout, QTextEdit, QApplication, QMessageBox)
+    QHBoxLayout, QTextEdit, QApplication, QMessageBox, QAbstractItemView)
 
 from calibre.ebooks.oeb.polish.container import get_container
 from calibre.ebooks.oeb.polish.fonts import font_family_data, change_font
@@ -253,7 +253,7 @@ class ManageFonts(Dialog):
         fv.setSortingEnabled(True)
         fv.setShowGrid(False)
         fv.setAlternatingRowColors(True)
-        fv.setSelectionMode(fv.ExtendedSelection)
+        fv.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         fv.setSelectionBehavior(fv.SelectRows)
         fv.horizontalHeader().setSortIndicator(1, Qt.SortOrder.AscendingOrder)
         self.container = c = QWidget()
diff --git a/src/calibre/gui2/tweak_book/polish.py b/src/calibre/gui2/tweak_book/polish.py
index 8eee5df25b..71c00ce656 100644
--- a/src/calibre/gui2/tweak_book/polish.py
+++ b/src/calibre/gui2/tweak_book/polish.py
@@ -12,7 +12,7 @@ from PyQt5.Qt import (
     QTextBrowser, QVBoxLayout, QDialog, QDialogButtonBox, QIcon, QLabel,
     QCheckBox, Qt, QListWidgetItem, QHBoxLayout, QListWidget, QPixmap,
     QSpinBox, QStyledItemDelegate, QSize, QStyle, QPen,
-    QProgressBar, pyqtSignal, QApplication
+    QProgressBar, pyqtSignal, QApplication, QAbstractItemView
 )
 
 from calibre import human_readable, fit_image, force_unicode
@@ -185,7 +185,7 @@ class CompressImages(Dialog):
         for name in sorted(get_compressible_images(c), key=numeric_sort_key):
             x = QListWidgetItem(name, i)
             x.setData(Qt.ItemDataRole.UserRole, c.filesize(name))
-        i.setSelectionMode(i.ExtendedSelection)
+        i.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         i.setMinimumHeight(350), i.setMinimumWidth(350)
         i.selectAll(), i.setSpacing(5)
         self.delegate = ImageItemDelegate(self)
diff --git a/src/calibre/gui2/tweak_book/preferences.py b/src/calibre/gui2/tweak_book/preferences.py
index 07cba73ed2..3dc79417e2 100644
--- a/src/calibre/gui2/tweak_book/preferences.py
+++ b/src/calibre/gui2/tweak_book/preferences.py
@@ -18,7 +18,7 @@ from PyQt5.Qt import (
     QDialog, QGridLayout, QStackedWidget, QDialogButtonBox, QListWidget,
     QListWidgetItem, QIcon, QWidget, QSize, QFormLayout, Qt, QSpinBox,
     QCheckBox, pyqtSignal, QDoubleSpinBox, QComboBox, QLabel, QFont, QApplication,
-    QFontComboBox, QPushButton, QSizePolicy, QHBoxLayout, QGroupBox,
+    QFontComboBox, QPushButton, QSizePolicy, QHBoxLayout, QGroupBox, QAbstractItemView,
     QToolButton, QVBoxLayout, QSpacerItem, QTimer, QRadioButton)
 
 from calibre import prepare_string_for_xml
@@ -434,7 +434,7 @@ class ToolbarList(QListWidget):
 
     def __init__(self, parent=None):
         QListWidget.__init__(self, parent)
-        self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
 
 
 class ToolbarSettings(QWidget):
diff --git a/src/calibre/gui2/tweak_book/reports.py b/src/calibre/gui2/tweak_book/reports.py
index 39b8ccb079..7ef8c3bfba 100644
--- a/src/calibre/gui2/tweak_book/reports.py
+++ b/src/calibre/gui2/tweak_book/reports.py
@@ -20,7 +20,7 @@ from PyQt5.Qt import (
     QListWidgetItem, QLineEdit, QStackedWidget, QSplitter, QByteArray, QPixmap,
     QStyledItemDelegate, QModelIndex, QRect, QStyle, QPalette, QTimer, QMenu,
     QAbstractItemModel, QTreeView, QFont, QRadioButton, QHBoxLayout,
-    QFontDatabase, QComboBox, QUrl)
+    QFontDatabase, QComboBox, QUrl, QAbstractItemView)
 
 from calibre import human_readable, fit_image
 from calibre.constants import DEBUG
@@ -130,7 +130,8 @@ class FilesView(QTableView):
 
     def __init__(self, model, parent=None):
         QTableView.__init__(self, parent)
-        self.setSelectionBehavior(self.SelectRows), self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionBehavior(self.SelectRows)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.setAlternatingRowColors(True)
         self.setSortingEnabled(True)
         self.proxy = p = ProxyModel(self)
diff --git a/src/calibre/gui2/tweak_book/search.py b/src/calibre/gui2/tweak_book/search.py
index 34195357d7..9fe34592bd 100644
--- a/src/calibre/gui2/tweak_book/search.py
+++ b/src/calibre/gui2/tweak_book/search.py
@@ -14,7 +14,7 @@ from PyQt5.Qt import (
     QGridLayout, QHBoxLayout, QIcon, QItemSelection, QKeySequence, QLabel, QLineEdit,
     QListView, QMenu, QMimeData, QModelIndex, QPushButton, QScrollArea, QSize,
     QSizePolicy, QStackedLayout, QStyledItemDelegate, Qt, QTimer, QToolBar,
-    QToolButton, QVBoxLayout, QWidget, pyqtSignal
+    QToolButton, QVBoxLayout, QWidget, pyqtSignal, QAbstractItemView
 )
 
 from calibre import prepare_string_for_xml
@@ -912,7 +912,7 @@ class SavedSearches(QWidget):
         self.model.dataChanged.connect(self.show_details)
         searches.setModel(self.model)
         searches.selectionModel().currentChanged.connect(self.show_details)
-        searches.setSelectionMode(searches.ExtendedSelection)
+        searches.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.delegate = SearchDelegate(searches)
         searches.setItemDelegate(self.delegate)
         searches.setAlternatingRowColors(True)
diff --git a/src/calibre/gui2/tweak_book/spell.py b/src/calibre/gui2/tweak_book/spell.py
index 2e680856d2..65da759548 100644
--- a/src/calibre/gui2/tweak_book/spell.py
+++ b/src/calibre/gui2/tweak_book/spell.py
@@ -16,7 +16,7 @@ from PyQt5.Qt import (
     QInputDialog, QKeySequence, QLabel, QLineEdit, QListWidget, QListWidgetItem,
     QMenu, QModelIndex, QPlainTextEdit, QPushButton, QSize, QStackedLayout, Qt,
     QTableView, QTimer, QToolButton, QTreeWidget, QTreeWidgetItem, QVBoxLayout,
-    QWidget, pyqtSignal
+    QWidget, pyqtSignal, QAbstractItemView
 )
 from threading import Thread
 
@@ -216,7 +216,7 @@ class ManageUserDictionaries(Dialog):
         self.la = la = QLabel(_('Words in this dictionary:'))
         l.addWidget(la)
         self.words = w = UserWordList(self)
-        w.setSelectionMode(w.ExtendedSelection)
+        w.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         l.addWidget(w)
         self.add_word_button = b = QPushButton(_('&Add word'), self)
         b.clicked.connect(self.add_word)
diff --git a/src/calibre/gui2/viewer/highlights.py b/src/calibre/gui2/viewer/highlights.py
index 0cf65f9feb..4a6454a186 100644
--- a/src/calibre/gui2/viewer/highlights.py
+++ b/src/calibre/gui2/viewer/highlights.py
@@ -10,7 +10,8 @@ from itertools import chain
 from PyQt5.Qt import (
     QColor, QFont, QHBoxLayout, QIcon, QImage, QItemSelectionModel, QKeySequence,
     QLabel, QMenu, QPainter, QPainterPath, QPixmap, QPushButton, QRect, QSizePolicy,
-    Qt, QTextEdit, QTreeWidget, QTreeWidgetItem, QVBoxLayout, QWidget, pyqtSignal
+    Qt, QTextEdit, QTreeWidget, QTreeWidgetItem, QVBoxLayout, QWidget, pyqtSignal,
+    QAbstractItemView
 )
 
 from calibre.constants import (
@@ -156,7 +157,7 @@ class Highlights(QTreeWidget):
         self.default_decoration = QIcon(I('blank.png'))
         self.setHeaderHidden(True)
         self.num_of_items = 0
-        self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         set_no_activate_on_click(self)
         self.itemActivated.connect(self.item_activated)
         self.currentItemChanged.connect(self.current_item_changed)
diff --git a/src/calibre/gui2/viewer/toolbars.py b/src/calibre/gui2/viewer/toolbars.py
index 27ef167af6..c5588914c1 100644
--- a/src/calibre/gui2/viewer/toolbars.py
+++ b/src/calibre/gui2/viewer/toolbars.py
@@ -8,7 +8,8 @@ from functools import partial
 
 from PyQt5.Qt import (
     QAction, QGroupBox, QHBoxLayout, QIcon, QKeySequence, QLabel, QListWidget,
-    QListWidgetItem, QMenu, Qt, QToolBar, QToolButton, QVBoxLayout, pyqtSignal
+    QListWidgetItem, QMenu, Qt, QToolBar, QToolButton, QVBoxLayout, pyqtSignal,
+    QAbstractItemView
 )
 from PyQt5.QtWebEngineWidgets import QWebEnginePage
 
@@ -305,7 +306,7 @@ class ActionsList(QListWidget):
 
     def __init__(self, actions, parent=None, is_source=True):
         QListWidget.__init__(self, parent)
-        self.setSelectionMode(self.ExtendedSelection)
+        self.setSelectionMode(QAbstractItemView.SelectionMode.ExtendedSelection)
         self.setDragEnabled(True)
         self.viewport().setAcceptDrops(True)
         self.setDropIndicatorShown(True)