diff --git a/src/calibre/gui2/viewer/config.py b/src/calibre/gui2/viewer/config.py
index 5439cddad4..02ee94bcdb 100644
--- a/src/calibre/gui2/viewer/config.py
+++ b/src/calibre/gui2/viewer/config.py
@@ -111,6 +111,13 @@ def save_viewer_profile(profile_name, profile, *user_names: str):
         profile = json.loads(profile)
     if isinstance(profile, dict):
         profile['__timestamp__'] = isoformat(utcnow())
+        from calibre.gui2.viewer.toolbars import current_actions, DEFAULT_ACTIONS
+        ca = current_actions()
+        s = {}
+        if ca != DEFAULT_ACTIONS:
+            s['toolbar-actions'] = ca
+        if s:
+            profile['__standalone_extra_settings__'] = s
     try:
         with open(os.path.join(viewer_config_dir, 'profiles.json'), 'rb') as f:
             raw = json.loads(f.read())
diff --git a/src/calibre/gui2/viewer/toolbars.py b/src/calibre/gui2/viewer/toolbars.py
index 3fe1c1493f..5b0403f588 100644
--- a/src/calibre/gui2/viewer/toolbars.py
+++ b/src/calibre/gui2/viewer/toolbars.py
@@ -152,6 +152,7 @@ class ActionsToolBar(ToolBar):
         web_view.read_aloud_state_changed.connect(self.update_read_aloud_action)
         web_view.customize_toolbar.connect(self.customize, type=Qt.ConnectionType.QueuedConnection)
         web_view.view_created.connect(self.on_view_created)
+        web_view.change_toolbar_actions.connect(self.change_toolbar_actions)
 
         self.web_actions = {}
         self.back_action = a = shortcut_action('back')
@@ -223,6 +224,13 @@ class ActionsToolBar(ToolBar):
 
         self.add_actions()
 
+    def change_toolbar_actions(self, toolbar_actions):
+        if toolbar_actions is None:
+            vprefs.__delitem__('actions-toolbar-actions')
+        else:
+            vprefs.set('actions-toolbar-actions', toolbar_actions)
+        self.add_actions()
+
     def update_web_action(self):
         a = self.sender()
         for x, ac in self.web_actions.items():
diff --git a/src/calibre/gui2/viewer/web_view.py b/src/calibre/gui2/viewer/web_view.py
index 86160761e0..ec91e08684 100644
--- a/src/calibre/gui2/viewer/web_view.py
+++ b/src/calibre/gui2/viewer/web_view.py
@@ -492,6 +492,7 @@ class WebView(RestartingWebEngineView):
     standalone_misc_settings_changed = pyqtSignal(object)
     view_created = pyqtSignal(object)
     content_file_changed = pyqtSignal(str)
+    change_toolbar_actions = pyqtSignal(object)
 
     def __init__(self, parent=None):
         self._host_widget = None
@@ -581,6 +582,11 @@ class WebView(RestartingWebEngineView):
             self.execute_when_ready('profile_response', 'apply-profile', settings)
         elif which == 'request-save':
             self.execute_when_ready('profile_response', 'request-save', profile_name)
+        elif which == 'apply-profile-to-viewer-ui':
+            toolbar_actions = None
+            s = settings.get('__standalone_extra_settings__', {})
+            toolbar_actions = s.get('toolbar-actions', None)
+            self.change_toolbar_actions.emit(toolbar_actions)
 
     def link_hovered(self, url):
         if url == 'javascript:void(0)':
diff --git a/src/pyj/read_book/profiles.pyj b/src/pyj/read_book/profiles.pyj
index e7800b7b11..1feffa5062 100644
--- a/src/pyj/read_book/profiles.pyj
+++ b/src/pyj/read_book/profiles.pyj
@@ -38,11 +38,12 @@ def use_profile(container_id, profile_name, profile_data):
         return
     sd = get_session_data()
     apply_reader_profile(sd, profile_data)
+    if ui_operations.apply_profile:
+        ui_operations.apply_profile(profile_data)
     container.dispatchEvent(new Event('settings_changed'))
     container.dispatchEvent(new Event('close_panel'))
 
 
-
 def delete_profile(container_id, profile_name):
     question_dialog(_('Are you sure?'), _('Are you sure you want to delete the saved profile named: {}?').format(profile_name),
         def (ok):
diff --git a/src/pyj/viewer-main.pyj b/src/pyj/viewer-main.pyj
index 4fddef9538..b9d3d91866 100644
--- a/src/pyj/viewer-main.pyj
+++ b/src/pyj/viewer-main.pyj
@@ -89,6 +89,7 @@ def profile_response(which, x):
         apply_reader_profile(sd, x)
         if view:
             view.preferences_changed()
+        ui_operations.apply_profile(x)
     elif which is 'request-save':
         sd = get_session_data()
         settings = settings_for_reader_profile(sd)
@@ -371,6 +372,8 @@ if window is window.top:
         install(TRANSLATIONS_DATA)
     ui_operations.get_all_profiles = get_all_profiles
     ui_operations.save_profile = save_profile
+    ui_operations.apply_profile = def(profile):
+        to_python.profile_op('apply-profile-to-viewer-ui', "", profile)
     ui_operations.get_file = get_file
     ui_operations.get_url_for_book_file_name = get_url_for_book_file_name
     ui_operations.get_mathjax_files = get_mathjax_files