diff --git a/manual/mathjax.html b/manual/mathjax.html
index 0cf8c1f8b1..88047e6023 100644
--- a/manual/mathjax.html
+++ b/manual/mathjax.html
@@ -8,7 +8,7 @@
 <!-- This script tag is needed to make calibre's ebook-viewer recpgnize that this file needs math typesetting -->
 <script type="text/x-mathjax-config">
     // This line adds numbers to all equations automatically, unless explicitly suppressed.
-    MathJax.Hub.Config({ TeX: { equationNumbers: {autoNumber: "all"} } });
+    MathJax.tex = {tags: 'all'};
 </script>
 
 <style>
diff --git a/manual/resources/mathjax.epub b/manual/resources/mathjax.epub
index 09b1e45b01..1b7b2a061e 100644
Binary files a/manual/resources/mathjax.epub and b/manual/resources/mathjax.epub differ
diff --git a/setup/mathjax.py b/setup/mathjax.py
index 15f927010b..d9afda850a 100644
--- a/setup/mathjax.py
+++ b/setup/mathjax.py
@@ -7,7 +7,6 @@ __copyright__ = '2012, Kovid Goyal <kovid at kovidgoyal.net>'
 __docformat__ = 'restructuredtext en'
 
 import os, json
-from io import BytesIO
 from hashlib import sha1
 
 
@@ -19,9 +18,8 @@ class MathJax(ReVendor):
     description = 'Create the MathJax bundle'
     NAME = 'mathjax'
     TAR_NAME = 'MathJax'
-    VERSION = '2.7.6'
+    VERSION = '3.0.5'
     DOWNLOAD_URL = 'https://github.com/mathjax/MathJax/archive/%s.tar.gz' % VERSION
-    FONT_FAMILY = 'TeX'
 
     def add_file_pre(self, name, raw):
         self.h.update(raw)
@@ -46,14 +44,10 @@ class MathJax(ReVendor):
         with self.temp_dir(suffix='-calibre-mathjax-build') as tdir:
             src = opts.path_to_mathjax or self.download_vendor_release(tdir, opts.mathjax_url)
             self.info('Adding MathJax...')
-            unpacked = 'unpacked' if self.e(self.j(src, 'unpacked')) else ''
-            self.add_file(self.j(src, unpacked, 'MathJax.js'), 'MathJax.js')
+            for x in 'core loader startup input/tex-full input/asciimath input/mml input/mml/entities output/chtml'.split():
+                self.add_file(self.j(src, 'es5', x + '.js'), x + '.js')
             self.add_tree(
-                self.j(src, 'fonts', 'HTML-CSS', self.FONT_FAMILY, 'woff'),
-                'fonts/HTML-CSS/%s/woff' % self.FONT_FAMILY,
-                lambda x: not x.endswith('.woff'))
-            for d in 'extensions jax/element jax/input jax/output/CommonHTML'.split():
-                self.add_tree(self.j(src, unpacked, *d.split('/')), d)
+                self.j(src, 'es5', 'output', 'chtml'), 'output/chtml')
             etag = self.h.hexdigest()
             with open(self.j(self.RESOURCES, 'mathjax', 'manifest.json'), 'wb') as f:
                 f.write(json.dumps({'etag': etag, 'files': self.mathjax_files, 'version': self.VERSION}, indent=2).encode('utf-8'))
diff --git a/src/calibre/gui2/viewer/mathjax.py b/src/calibre/gui2/viewer/mathjax.py
deleted file mode 100644
index 121e9d4e76..0000000000
--- a/src/calibre/gui2/viewer/mathjax.py
+++ /dev/null
@@ -1,72 +0,0 @@
-#!/usr/bin/env python2
-# vim:fileencoding=utf-8
-# License: GPL v3 Copyright: 2018, Kovid Goyal <kovid at kovidgoyal.net>
-
-from __future__ import absolute_import, division, print_function, unicode_literals
-
-PATCHED_MATHJAX = '''
-
-function postprocess_mathjax(link_uid) {
-    Array.prototype.forEach.call(document.getElementsByTagName('a'), function(a) {
-        var href = a.getAttribute('href');
-        if (href && href.startsWith('#')) {
-            a.setAttribute('href', 'javascript: void(0)')
-            a.setAttribute('data-' + link_uid, JSON.stringify({'frag':href.slice(1)}))
-        }
-    });
-    document.documentElement.dispatchEvent(new CustomEvent("calibre-mathjax-init-done"));
-}
-
-function monkeypatch(mathjax_files) {
-    var orig = window.MathJax.Ajax.fileURL.bind(window.MathJax.Ajax);
-    var StyleString = window.MathJax.Ajax.StyleString.bind(window.MathJax.Ajax);
-
-    window.MathJax.Ajax.StyleString = function(styles) {
-        return StyleString(styles).replace(/url\\('?(.*?)'?\\)/g, function(match, url) {
-            if (!url.endsWith('.woff')) return match;
-            url = mathjax_files[url];
-            if (!url) return match;
-            if (typeof url != "string") {
-                url = window.URL.createObjectURL(url);
-                mathjax_files[name] = url;
-            }
-            return "url('" + url + "')";
-        });
-    }
-
-    window.MathJax.Ajax.fileURL = function(mathjax_name) {
-        var ans = orig(mathjax_name);
-        var name = ans.replace(/^\\//g, '');
-        if (name.startsWith('../fonts')) name = name.slice(3);
-        ans = mathjax_files[name];
-        if (!ans) ans = name;
-        if (typeof ans !== 'string') {
-            mathjax_files[name] = window.URL.createObjectURL(ans);
-            ans = mathjax_files[name];
-        }
-        if (ans === name && !name.startsWith('blob:') && !name.endsWith('/eot') && !name.endsWith('/woff') && !name.endsWith('/otf')) {
-            if (ans.endsWith('.eot') || ans.endsWith('.otf')) ans = '';
-            else console.log('WARNING: Failed to resolve MathJax file: ' + mathjax_name);
-        }
-        return ans;
-    }
-    window.MathJax.Ajax.fileRev = function(mathjax_name) { return ''; }
-}
-
-function init_mathjax(link_uid, mathjax_files) {
-    monkeypatch(mathjax_files);
-    window.MathJax.Hub.Register.StartupHook("End", postprocess_mathjax.bind(this, link_uid))
-}
-
-document.documentElement.addEventListener("calibre-mathjax-init", function(ev) {
-
-window.MathJax = ev.detail.MathJax;
-window.MathJax.AuthorInit = init_mathjax.bind(this, ev.detail.link_uid, ev.detail.mathjax_files);
-
-__SRC__
-});
-'''
-
-
-def monkeypatch_mathjax(src):
-    return PATCHED_MATHJAX.replace('__SRC__', src, 1)
diff --git a/src/calibre/gui2/viewer/web_view.py b/src/calibre/gui2/viewer/web_view.py
index 371df57b61..62e568c257 100644
--- a/src/calibre/gui2/viewer/web_view.py
+++ b/src/calibre/gui2/viewer/web_view.py
@@ -121,7 +121,6 @@ class UrlSchemeHandler(QWebEngineUrlSchemeHandler):
     def __init__(self, parent=None):
         QWebEngineUrlSchemeHandler.__init__(self, parent)
         self.mathjax_dir = P('mathjax', allow_user_override=False)
-        self.mathjax_manifest = None
         self.allowed_hosts = (FAKE_HOST, SANDBOX_HOST)
 
     def requestStarted(self, rq):
@@ -132,7 +131,7 @@ class UrlSchemeHandler(QWebEngineUrlSchemeHandler):
         if host not in self.allowed_hosts or url.scheme() != FAKE_PROTOCOL:
             return self.fail_request(rq)
         name = url.path()[1:]
-        if host == SANDBOX_HOST and not name.startswith('book/'):
+        if host == SANDBOX_HOST and name.partition('/')[0] not in ('book', 'mathjax'):
             return self.fail_request(rq)
         if name.startswith('book/'):
             name = name.partition('/')[2]
@@ -169,14 +168,6 @@ class UrlSchemeHandler(QWebEngineUrlSchemeHandler):
             else:
                 rq.fail(rq.UrlNotFound)
         elif name.startswith('mathjax/'):
-            from calibre.gui2.viewer.mathjax import monkeypatch_mathjax
-            if name == 'mathjax/manifest.json':
-                if self.mathjax_manifest is None:
-                    import json
-                    from calibre.srv.books import get_mathjax_manifest
-                    self.mathjax_manifest = as_bytes(json.dumps(get_mathjax_manifest()['files']))
-                send_reply(rq, 'application/json', self.mathjax_manifest)
-                return
             path = os.path.abspath(os.path.join(self.mathjax_dir, '..', name))
             if path.startswith(self.mathjax_dir):
                 mt = guess_type(name)
@@ -186,10 +177,35 @@ class UrlSchemeHandler(QWebEngineUrlSchemeHandler):
                 except EnvironmentError as err:
                     prints("Failed to get mathjax file: {} with error: {}".format(name, err))
                     return self.fail_request(rq, rq.RequestFailed)
-                if 'MathJax.js' in name:
-                    # raw = open(os.path.expanduser('~/work/mathjax/unpacked/MathJax.js')).read()
-                    raw = monkeypatch_mathjax(raw.decode('utf-8')).encode('utf-8')
-
+                if name.endswith('/startup.js'):
+                    raw = b'''
+                    window.MathJax = {};
+                    window.MathJax.options = {
+                        renderActions: {
+                            // disable the mathjax context menu
+                            addMenu: [0, '', ''],
+                        },
+                    };
+                    window.MathJax.loader = {
+                        load: ['input/tex-full', 'input/asciimath', 'input/mml', 'output/chtml'],
+                    };
+                    window.MathJax.startup = {
+                        ready: () => {
+                            MathJax.startup.defaultReady();
+                            MathJax.startup.promise.then(() => {
+                                document.documentElement.dispatchEvent(new CustomEvent("calibre-mathjax-typeset-done"));
+                            });
+                        },
+                    };
+                    for (const s of document.scripts) {
+                        if (s.type === "text/x-mathjax-config") {
+                            es = document.createElement('script');
+                            es.text = s.text;
+                            document.head.appendChild(es);
+                            document.head.removeChild(es);
+                        }
+                    }
+                    ''' + raw
                 send_reply(rq, mt, raw)
         elif not name:
             send_reply(rq, 'text/html', viewer_html())
diff --git a/src/pyj/read_book/mathjax.pyj b/src/pyj/read_book/mathjax.pyj
index 1de72145b1..b91c720a72 100644
--- a/src/pyj/read_book/mathjax.pyj
+++ b/src/pyj/read_book/mathjax.pyj
@@ -16,75 +16,20 @@ def get_url(mathjax_files, name):
     return ans
 
 
-def monkeypatch(mathjax_files):
-    StyleString = window.MathJax.Ajax.StyleString.bind(window.MathJax.Ajax)
-
-    def style_string(styles):
-        # replace the URLs in the generated stylesheet
-        return StyleString(styles).replace(/url\('?(.*?)'?\)/g, def (match, url):
-            if not url.endsWith('.woff'):
-                return match
-            url = get_url(mathjax_files, url)
-            ans = f"url('{url}')"
-            return ans
-        )
-
-    orig = window.MathJax.Ajax.fileURL.bind(window.MathJax.Ajax)
-    def file_url(file):
-        ans = orig(file)
-        name = ans.lstrip('/')
-        if name.startswith('../fonts'):
-            name = name[3:]
-        if name.rpartition('/')[-1] in 'otf eot woff':
-            return name
-        ans = get_url(mathjax_files, name)
-        if ans is name and not name.startswith('blob:'):
-            if ans.endswith('.eot') or ans.endswith('.otf'):
-                return ''
-            print('WARNING: Failed to resolve MathJax file:', name)
-        return ans
-    window.MathJax.Ajax.fileURL = file_url
-    window.MathJax.Ajax.StyleString = style_string
-    window.MathJax.Ajax.fileRev = def(file):
-        return ''
-
-def postprocess(link_uid, proceed):
+def postprocess(link_uid):
     for a in document.getElementsByTagName('a'):
         href = a.getAttribute('href')
         if href.startswith('#'):
             a.setAttribute('href', 'javascript: void(0)')
             a.setAttribute('data-' + link_uid, JSON.stringify({'frag':href[1:]}))
-    proceed()
 
-def init_mathjax(mathjax_files, link_uid, proceed):
-    monkeypatch(mathjax_files)
-    window.MathJax.Hub.Register.StartupHook("End", postprocess.bind(this, link_uid, proceed))
 
 def apply_mathjax(mathjax_files, link_uid, proceed):
-    window.MathJax = m = v'{}'
-    m.positionToHash = False
-    m.showMathMenu = False
-    m.showMathMenuMSIE = False
-    m.extensions = "tex2jax.js asciimath2jax.js mml2jax.js".split(' ')
-    m.jax = "input/TeX input/MathML input/AsciiMath output/CommonHTML".split(' ')
-    m.TeX = v'{}'
-    m.TeX.extensions = "AMSmath.js AMSsymbols.js noErrors.js noUndefined.js".split(' ')
-    m.CommonHTML = v'{ linebreaks: { automatic: true} }'
+    document.documentElement.addEventListener("calibre-mathjax-typeset-done", def(ev):
+        postprocess(link_uid)
+        proceed()
+    )
     script = E.script(type='text/javascript')
+    script.async = True
+    script.src = f'{runtime.FAKE_PROTOCOL}://{runtime.SANDBOX_HOST}/mathjax/startup.js'
     document.head.appendChild(script)
-    if runtime.is_standalone_viewer:
-        script.onload = def():
-            ev = new CustomEvent("calibre-mathjax-init", {
-                'detail': {
-                    'MathJax': m,
-                    'link_uid': link_uid,
-                    'mathjax_files': mathjax_files,
-                }
-            })
-            document.documentElement.dispatchEvent(ev)
-        document.documentElement.addEventListener("calibre-mathjax-init-done", def(ev):
-            proceed()
-        )
-    else:
-        m.AuthorInit = init_mathjax.bind(this, mathjax_files, link_uid, proceed)
-    script.src = get_url(mathjax_files, 'MathJax.js')
diff --git a/src/pyj/viewer-main.pyj b/src/pyj/viewer-main.pyj
index 9c510dd48f..154f6ffa57 100644
--- a/src/pyj/viewer-main.pyj
+++ b/src/pyj/viewer-main.pyj
@@ -63,58 +63,9 @@ def get_file(book, name, proceed):
         xhr.responseType = 'blob'
     xhr.send()
 
-def mathjax_file_received(name, proceed, end_type, xhr, ev):
-    end_type = workaround_qt_bug(xhr, end_type)
-    if end_type is 'abort':
-        return
-    if end_type is not 'load':
-        show_error(_('Failed to load MathJax file'), _(
-            'Could not load the file: {} with error: {}').format(name, xhr.error_html))
-        return
-    if not xhr.responseType or xhr.responseType is 'text':
-        result = xhr.responseText
-    else if xhr.responseType is 'blob' or xhr.responseType is 'json':
-        result = xhr.response
-    else:
-        show_error(_('Failed to load MathJax file'), _(
-            'Could not load the file: {} unknown response type: {}')
-.format(name, xhr.responseType))
-        return
-    if name is 'manifest.json':
-        get_mathjax_files.manifest = result
-        get_mathjax_files_stage2.files_to_get = list(Object.keys(result))
-        get_mathjax_files_stage2.file_data = {}
-        get_mathjax_files_stage2(proceed)
-        return
-
-    get_mathjax_files_stage2.file_data[name] = result
-    get_mathjax_files_stage2.files_to_get.remove(name)
-    if not get_mathjax_files_stage2.files_to_get.length:
-        proceed(get_mathjax_files_stage2.file_data)
-
-def get_mathjax_manifest(proceed):
-    xhr = ajax('mathjax/manifest.json', mathjax_file_received.bind(None, 'manifest.json', proceed), ok_code=0)
-    xhr.responseType = 'json'
-    xhr.send()
-
-
-def get_mathjax_files_stage2(proceed):
-    if not get_mathjax_files_stage2.files_to_get.length:
-        proceed(get_mathjax_files_stage2.file_data)
-        return
-    for filename in get_mathjax_files_stage2.files_to_get:
-        xhr = ajax(f'mathjax/{filename}', mathjax_file_received.bind(None, filename, proceed), ok_code=0)
-        xhr.responseType = 'blob'
-        xhr.send()
-
-
 
 def get_mathjax_files(proceed):
-    if not get_mathjax_files.manifest:
-        get_mathjax_manifest(proceed)
-    else:
-        get_mathjax_files_stage2(proceed)
-
+    proceed({})
 
 
 def update_url_state(replace):